Which nucleus of the hypothalamus receives stress-related information from the amygdala?

The paraventricular nucleus of the hypothalamus plays a crucial role in the response to stress by integrating information from various brain regions, including the amygdala, which is key for processing emotions and stress-related stimuli. The paraventricular nucleus is particularly important for the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. When the amygdala perceives a stressor, it sends signals to the paraventricular nucleus, which then helps to initiate the release of corticotropin-releasing hormone (CRH). This hormone triggers the adrenal glands to produce cortisol, a primary stress hormone that helps the body respond to stress.

In contrast, the medial preoptic nucleus is primarily involved in the regulation of reproductive behaviors and thermoregulation. The lateral hypothalamic area is more associated with feeding behavior and arousal. The suprachiasmatic nucleus functions primarily as the body’s master clock, regulating circadian rhythms rather than specifically processing stress-related information. Thus, the paraventricular nucleus stands out as the key center for receiving and acting on stress-related signals from the amygdala.